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Department of Biological Science and Technology
National Chiao Tung University
Office: (03) 571-2121 X
56948 or 56939 (Secretary)
Email:
mao1010@ms7.hinet.net
Course Website:
Biotechnology & Biomedicine seminar in English
Date of Birth: October 10,
1946 |
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EDUCATION |
POSITIONS |
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B.S. |
Biochemistry, Fu-Jen University, Taiwan |
1965 - 1969 |
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M.S. |
Immunochemistry,The University of Southwestern Louisiana |
1970 - 1972 |
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Ph.D. |
Biochemistry, Department of Medicine/Department of Cell
Biology, Baylor College of Medicine, Houston, Texas |
1973 - 1977 |
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SCIENTIFIC ACHIEVEMENT |
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Published more than 100
peer-reviewed papers and 130 world-wide patents |
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MAJOR RESEARCH INTEREST
Gene Therapy
Biotechnology
Pharmaceutical-Drug
Research and Development
Atherosclerosis, Restenosis, Hypertrophic
Cardiomyopathy, Ischemia, and Thrombosis
the
Lipid and Lipoprotein Metabolism, Immunochemistry, and
Clinical Chemistry
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ADMINISTRATIVE EXPERIENCE
Excellent skill to motivate
and teach others
Department Head, CEO,
Project, program, and group leader
Board of scientific councils
Strategic planning
Pre-clinical preparation
Coordination with research
and development
Submission for FDA 510K
approval
Patent preparation
Grant application
Editorial board member
Journal reviewer: J Biol
Chem, Biochemistry, J med Chem, Anal Chem, Clin Chem,
J Lipid Res, Arteriosclerosis and Thrombosis, Metabolism,
Biochim Biophy Acta
Medical school teaching
Ph.D. student thesis advisor
and committee member
校外：
總統府：生物科技委員會委員
工研院能資所：「高效率簡易固相萃取濃縮酵素膠片之開發」計畫顧問（91/2/1至91/7/31 止）
校內：
94學年度「校教評委員會」委員
94學年度「院教評委員會」委員
94學年度「經費稽核委員會」委員
94學年度「研究生獎助學金管理委員會」委員
94學年度「校務規劃委員會」委員
94學年度「理學院網路學習碩士在職專班委員會」委員
94學年度「招生委員會」常務委員
94學年度「職工申訴評議委員會」委員
96學年度「校教評委員會」委員
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National Chiao-Tung University, Hsinchu, Taiwan |
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Chair Professor, College of Biological Science and
Technology |
2007.8-2009 |
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國立交通大學,
生物科技學院講座教授 |
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National Chiao-Tung University, Hsinchu, Taiwan |
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Dean, College of Biological Science and Technology |
2003-2007.8 |
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國立交通大學,
生物科技學院院長 |
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National Chiao-Tung University, Hsinchu, Taiwan |
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Director, Institute of Biochemical Engineering |
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國立交通大學,
生化工程所所長 |
2000-2003 |
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Professor, Department of Biological Science and
Technology,
College of Sciences |
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National Chiao-Tung University, Hsinchu, Taiwan |
1997-2000 |
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Joint Professor, Institute of Biological Science and
Technology,
School of Graduate Studies |
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PIG RESEARCH INSTITUTE TAIWAN, Maioli, Chunan, Taiwan |
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Department Head of Applied Biological Sciences |
1995-2000 |
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Chief Executive Office, Cardiovascular Research Center |
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Department of Comparative Medicine |
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MARION MERRELL DOW, Cincinnati, OH |
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Head of Atherosclerosis Research Group |
1985-1994 |
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Department of Biochemical Sciences and Cardiovascular
Research |
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MOUNT SINAI SCHOOL OF MEDICINE, New York, NY |
1983-1984 |
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Associate Professor, Division of Cardiology,
Department of Medicine |
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MAYO CLINIC & MEDICAL SCHOOL, Rochester, MN |
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Assistant Professor, Department of Biochemistry |
1980-1982 |
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Associate Consultant, Atherosclerosis Research Unit,
Division of
Cardiovascular Diseases |
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MAYO CLINIC, Rochester, MN |
1979 |
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Research
Associate, Atherosclerosis Research Unit |
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BAYLOR COLLEGE OF
MEDICINE, Houston, TX |
1978-1979 |
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Research Associate, Department of Medicine |
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BAYLOR COLLEGE OF MEDICINE, Houston, TX |
1973-1977 |
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Graduate Student,
Department of Cell Biology and Medicine |
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THE UNIVERSITY OF
SOUTHWESTERN LOUISIANA, Lafayette, LA |
1970-1972 |
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Teaching Assistant and Graduate Student, Department of
Microbiology |
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RESEARCH AWARDS
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National Science Council Research project
(國科會個人型計畫主持人)
抗發炎分子haptoglobin在生理上之角色
(1/2),
計劃編碼:
NSC95-2313-B-009-003-MY2 |
2006-2008 |
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National Science Council Research project
(國科會個人型計畫主持人)
牛乳中β-lactoglobulin之生理功能(1/2),計劃編碼:
NSC94-2313-B-009-001
NT$1,379,000 |
2005-2007 |
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National Science Council Research project
(國科會個人型計畫主持人)
國內鮮牛乳β-lactoglobulin之大量損失對於生化及生理功能之影響,
計劃編碼:
NSC 93-2313-B-009-002
NT$1,348,700 |
2004-2005 |
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National Science Council Research project
(國科會個人型計畫主持人)
利用噬菌體重組抗體檢測牛乳品質 (2/2) ,
計劃編碼:
NSC92-2313-B-009-002
NT$1,614,410 |
2003-2005 |
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National Science Council Research project
(國科會個人型計畫主持人)
SARS病患臨床超快速檢測,計劃編碼:
NSC92-2751-B-009-001-Y
NT$2,581,200 |
2003-2004 |
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National Health Research Institute
Research project
(國衛院個人型計畫主持人)
(三年)
Role of haptoglobin in atherosclerosis,
計劃編碼:
NHRI-EX92-9229SI
NT$7,200,000 |
2003-2005 |
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Industrial Technology Research Institute
(工研院)
低密度膽固醇之免疫金製作技術開發
NT$500,000 |
2004-2004 |
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國朕生物科技蝦病毒快速檢測
NT$1,100,000 |
2001-2003 |
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National Science Council Research project
(國科會個人型計畫主持人)
Quality Control of Thermal-Processed Cow
Milk Using Recombinant Antibody from Phage Display,計劃編碼:
NSC 91-2313-B-009-001-
NT$3,600,000 |
2001-2004 |
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Cooperation of Research Program between
National NYMU and NCTU
Program project (陽明大學與交通大學跨領域合作研究計畫主持人)
Rapid Diagnosis of Cholesterol by
Bio-electronic optics. Program
Director
NT$1,000,000 |
2000-2001 |
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Council of Agriculture Program project
(農委會總計畫主持人)
Lactoferrin in Biotechnology,
Program Director
NT$ 9,000,000 / US$ 300,000 |
1999-2000 |
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National Science Council Research project
(國科會個人型計畫主持人)
Differentiation of biological response to
tumor using cloning animal in mice
Principal Investigator
NT$ 2,300,000 / US$ 76,000 |
1999-2001 |
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National Science Council Program project
(國科會整合型總計畫主持人)
Hypertrophic Cardiomyopathy in Swine.
Program Director
NT$ 24,000,000 / US$ 800,000 |
1998-2001 |
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National Science Council Program project
(國科會整合型總計畫主持人)
The Study of Porcine Hypertrophic
Cardiomyopathy.
Program Director
NT$ 60,000,000 / US$ 2,400,000 |
1995-1998 |
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Department of Health Program project (衛生署整合型總計畫主持人)
The Study of Comparative Medicine of
Cardiovascular Disease.
Program Director
NT$ 14,000,000 / US$ 560,000 |
1995-1998 |
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National Health of Research Institute
Contract grant (國衛院個人型計畫主持人)
Drug Selection for Atherosclerosis using
Lan Yu minipigs as an animal model
Principle Investigator
NT$8,500,000 /US$340,000 |
1996-1999 |
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Industrial Technology Research Institute,
Specific Targeting of Antihepatoma Drugs using LDL- and
Liposome-mediated Carrier.
Principal Investigator
NT$ 500,000 / US$ 20,000 |
1995-1996 |
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National Institutes of Health US NIH
Research grant
"Immunochemical Characterization of Human
Plasma Lipoproteins",
Principal Investigator
(HL‑32317): US$337,422
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1985-1988 |
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Awardee of Irma T. Hirschl Career
Scientist Award
New York
(First Place)
“Monoclonal Antibody Probes for Studying Human Plasma
Lipoproteins”
US$100,000 |
1984-1989 |
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National Institutes of Health US NIH
Research grant
"Immunochemical Characterization of Human
Plasma Lipoproteins",
Principal Investigator
(HL‑27114 and HL‑32317: US$126,000) |
1981-1984 |
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HONORS
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交通大學傑出人士榮譽獎勵 |
2007-2007 |
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Awardee of Outstanding/Achievement
Individual Award
2000
年國科會 (生物處) 個人傑出獎 (兩年)
From National Science Council (NT$
600,000) |
2000-2002 |
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Awardee of Outstanding/Achievement
Individual Award
1998年國科會
(生物處) 個人傑出獎 (兩年)
From National Science Council (NT$
600,000) |
1998-2000 |
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National Institutes of Health,
US
Awardee
of Research Career Development Award
(HL‑0048 and HL‑01306): US$201,300 |
1981-1986 |
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American Heart Association (Minnesota
Chapter) Grant-In-Aid Award
"Study of Lipolysis of Human Plasma
Lipoproteins",
Principle Investigator
(MHA-47):US$36,000 |
1980-1982 |
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US PATENTS ISSUED
(More than 130 issued world wide)
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1.
Mao SJT, Jackson RL.
Hypocholesterolemic and antiatherosclerotic uses of bis(3,5-di-
tertiary-butyl-4-hydroxyphenylthio)methane. US Patent 4,900,757
Feb. 13,1990
2. Mao SJT, Jackson RL.
Hypocholesterolemic use of bis(3,5-di-terteary-butly-4-
hydroxyphenylthio)methane. US Patent 4,954528 Sept.
4, 1990
3. Robinson. KM, Mao SJT,
Jackson RL. Method of treating diabetes mellitus. US
Patent 4,959,392 Sept. 25,1990
4. Robinson. KM, Mao SJT,
Parker RA. Jackson RL. Method of treating diabetes
mellitus with bisphenol derivatives. US Patent 5,001,282
March 19,1991
5. Robinson. KM, Mao SJT,
Parker RA. Jackson RL. Method of treating diabetes
mellitus with bisphenol derivatives. US Patent 5,0112,461
June 4, 1991
6. Mao SJT, Jackson RL.
Bis(alkyl-substituted-4-hydroxyphenylthio)alkane analogs as
inhibitors of anticatractogenesis. US Patent 5,061,734
Oct. 29,1991
7. Mao SJT, Jackson RL.
Bis(alkyl-substituted-4-hydroxyphenylthio)alkane analogs as
inhibitors of cataractogenesis. US Patent 5,112,870
May. 12, 1992
8. Mao SJT, Ku G, Jackson RL.
Hypotriglyceridemic use of certain bis(3,5-di-alkyl-4-
hydroxyphenylthio)methanes. US Patent 5,122,542 June
16,1992
9. Parker RA, Mao SJT.
2,6-di-alkyl-4-silyl-phenols as antiatherosclerotic agents.
US Patent 5,155,250 Oct. 13,1992
10. Krstenansky JL, Mao SJT.
Cyclic anticoagulant peptides. US Patent 5,192,745
March 9,1993
11. Krstenansky JL, Mao SJT.
Cyclic anticoagulant peptides. US Patent 5,236,898
Aug. 17,1993
12. Krstenansky JL, Mao SJT.
Radiolabeled anticoagulant peptides US Patent 5,279,812.
Jan. 18,1994
13. Parker RA, Mao SJT.
Bis[4-(2,6-di-alkyl)phenol]silane derivatives as antiathero-
sclerotic agents. US Patent 5,281,738 Jan.25,1994
14. Parker RA, Mao SJT.
Bis-[4-(2,6-di-alkyl)phenol]silane derivatives as antiathero-
sclerotic agents. US Patent 5,304,668 April 19,1994
15. Parker RA, Mao SJT.
2,6-di-alkyl-4-silyl-phenols as antiatherosclerotic agents.
US Patent 5,532,400 July 2,1996
16. Krstenansky JL, Mao SJT.
Stabilized sulfonate, sulfate, phosphonate and phosphate
derivatives of hirudin. US Patent 5,41,161 July
30,1996
17. Mao SJT, Yates MT,
Parker RA. Method of lowering serum cholesterol levels
with 2,6-dialky1-4-silyl-phenols. US Patent 5,677,291
Oct. 14,1997
18.
Krstenansky JL, Mao SJT.
Anticoagulant peptides. US Patent 5,789,540 Aug.4,1998
19.
Mao SJT, Yates MT, Parker RA.
Method of lowering serum cholesterol levels with
2,6-dI-alkyl-4-silyl-phenols. US patent 5,962,435
Oct. 5,1999
20.
Krstenansky, John L, Mao SJT.
Anticoagulant peptides. US Patent 6,005,071 Dec.21, 1999
21.
Mao SJT,
Krstenansky, JL.
Stabilisierte sulfonatund sulfatderivate von hirudin.
A.T.
Patent
2,191,02T Jun. 15, 2002
22.
Mao SJT,
Krstenansky, JL.
Stabilized sulfonate, sulfate, phosphonate and
phosphate derivatives of hirudin.
D.E.
Patent
691,330,33T Feb. 06, 2003
23.
Mao SJT,
Krstenansky, JL.
Stabilized sulfonate, sulfate, phosphonate and
phosphate derivatives of hirudin.
E.P.
Patent
0,443,429 Feb. 06, 2003
24.
Mao SJT,
Krstenansky, JL.
Stabilized sulfonate, sulfate, phosphonate and
phosphate derivatives of hirudin.
J.P.
Patent
4,211,097 Feb. 06, 2003
25.
Mao SJT,
Krstenansky, JL.
Stabilized sulfonate, sulfate, phosphonate and
phosphate derivatives of hirudin. I.E.
Patent
910,469 Feb. 06, 2003
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